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Symbol
Name
ID
Prrc2a
proline-rich coiled-coil 2A
MGI:1915467
Phenotype annotations related to nervous system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Polydipsia
Polyphagia
Disease(s) Associated with PRRC2A
type 1 diabetes mellitus

Mouse Phenotypes
nervous system phenotype
decreased oligodendrocyte progenitor number
abnormal brain morphology
abnormal brain development
increased brain weight
enlarged lateral ventricles
abnormal corpus callosum morphology
decreased astrocyte number
decreased oligodendrocyte number
abnormal astrocyte physiology
dysmyelination
decreased nerve conduction velocity
Availability Mouse Genotype
Prrc2atm1Fcw/Prrc2atm1Fcw
Tg(Nes-cre)1Kln/0  (conditional)
Prrc2atm1Fcw/Prrc2atm1Fcw
Olig2tm2(TVA,cre)Rth/Olig2+  (conditional)
*
Prrc2atm1Fcw/Prrc2atm1Fcw
Tg(Gfap-cre)77.6Mvs/0  (conditional)
*

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory